Fewer Shots, Same Success: A New IVF Protocol with Dr. Linnea Goodman

Written By Lora Shahine, MD

What if IVF didn’t have to mean so many shots? Could a new protocol allow for fewer shots, less office visits, AND be less expensive? 

In this episode of Brave & Curious, Dr. Lora Shahine is joined by Dr. Linnea Goodman to answer these questions and more. They review Dr. Goodman’s research into a protocol, not new to the fertility field around the world, but new to most listeners in the United States that has many benefits to IVF patients.

Dr. Linnea Goodman is a board-certified reproductive endocrinologist and infertility specialist. Throughout her career, Dr. Goodman has been dedicated to advancing the field of reproductive medicine through both clinical excellence and innovative research. Currently, Dr. Goodman practices at Virginia Fertility & IVF, where she specializes in minimally invasive office procedures aimed at optimizing fertility outcomes.

In this episode you’ll hear:

  • [1:16] Meet Dr. Linnea Goodman: reproductive endocrinologist and researcher

  • [2:24] IVF shots & their necessity

  • [4:45] Provera Protocol is a game-changer

  • [14:35] Research & evidence for the Provera Protocol 

  • [22:19] A patient-centered approach

  • [25:00] Research Outcomes

  • [27:07] Innovations in IVF: Progestins

  • [29:32 The patient experience: benefits and side effects of progestins

  • [32:36 What does the future hold? 

Resources mentioned: 

http://vafertility.com

Massin N, et al. New stimulation regimens: endogenous and exogenous progesterone use to block the LH surge during ovarian stimulation for IVF. Hum Reprod Update. 2017 Mar 1;23(2):211-220. doi: 10.1093/humupd/dmw047.PMID: 28062551 

R Beguería, et al. Medroxyprogesterone acetate versus ganirelix in oocyte donation: a randomized controlled trial. Hum Reprod. 2019 May 1;34(5):872-880 doi:10.1093/humrep/dez034. PMID: 30927417

Giles J, et al. Medroxyprogeseterone acetate is a useful alternative to a gonadotropin-releasing hormone antagonist in ooxyte-donation: a randomized controlled trial. Fert Stert 2021;116: 404-412. PMID: 33814126. DOI: 10.1016/j.fertnstert.2021.02.036

Welp A, et al. Oral medroxyprogesterone acetate for the use of ovulation suppression in in vitro fertilization: a cohort trial. Fertil Steril 2024 May;121(5):806-813. PMID: 38253117 DOI: 10.1016/j.fertnstert.2024.01.026

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Lora Shahine, MD

Dr. Lora Shahine, reproductive endocrinologist at Pacific NW Fertility and Clinical Assistant Professor at the University of Washington in Seattle, completed her residency in OBGYN at the University of California in San Francisco and fellowship in reproductive endocrinology at Stanford University. She is dedicated to educating and advocating for increased awareness of infertility, miscarriage, and the impact on environmental toxins on health through an active social media presence, teaching, clinical research, and authoring multiple blogs and books including best selling, ‘Not Broken: An Approachable Guide to Miscarriage and Recurrent Pregnancy Loss.’

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