Ovarian Rejuvenation: The Race to Extend Fertility with Roohi Jeelani, MD

What if the “final frontier” of fertility care is not IVF technology, but the aging ovary itself? Can science help improve egg quality, mitochondrial function, and reproductive lifespan? And how do patients sort through what is proven, what is promising, and what is still very much in the “ask your doctor before you try this” category?

In this episode of Brave & Curious, Dr. Lora Shahine welcomes reproductive endocrinologist Dr. Roohi Jeelani for a fascinating conversation about ovarian rejuvenation, age-related fertility decline, and the future of fertility treatment. 

Together, they discuss why age remains one of the biggest factors in IVF success, how egg quality changes over time, and why topics like oxidative stress, mitochondrial health, inflammation, and lifestyle optimization are becoming such important parts of the fertility conversation.

In this episode you’ll hear:

  • [1:07] Meet Dr. Roohi Jeelani

  • [2:32] Age and fertility

  • [4:23] Egg quality basics

  • [8:06] Sleep and fertility

  • [9:35] Stress and cortisol

  • [14:58] Movement and PCOS

  • [16:54] Nutrition for fertility

  • [18:51] Trimester zero prep: Small, sustainable changes

  • [29:25] CoQ10, Inositol, Melatonin

  • [35:38] NAD and egg quality

  • [43:56] GLP-1 fertility questions

  • [47:22] Peptides and PRP

  • [55:33] Ovarian rejuvenation research

  • [1:01:04] Future fertility medicine

Resources mentioned: 

onto.health

@roohijeelanimd on Instagram | LinkedIn

@onto-health-co on LinkedIn

Your Leggings Could be Causing Infertility? with Dr. Lora Shahine on YouTube

Can CoQ10 Improve Egg Quality and Sperm Health for TTC? with Dr. Lora Shahine on YouTube

Does Growth Hormone Improve IVF Outcomes? with Dr. Lora Shahine on YouTube

Dr. Shahine’s Weekly Newsletter on Fertility News and Recommendations

Follow @drlorashahine Instagram | YouTube | Tiktok | Her Books

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This episode was produced by Audiotocracy Podcast Production.

Lora Shahine, MD

Dr. Lora Shahine, reproductive endocrinologist at Pacific NW Fertility and Clinical Assistant Professor at the University of Washington in Seattle, completed her residency in OBGYN at the University of California in San Francisco and fellowship in reproductive endocrinology at Stanford University. She is dedicated to educating and advocating for increased awareness of infertility, miscarriage, and the impact on environmental toxins on health through an active social media presence, teaching, clinical research, and authoring multiple blogs and books including best selling, ‘Not Broken: An Approachable Guide to Miscarriage and Recurrent Pregnancy Loss.’

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